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Thrombophilia Guidelines

From Mohamed Bashir, originally posted November 17, 2012: What is the guideline for thrombophilia testing, how to test antithrombin (AT, antithrombin III, ATIII), protein C (PC), and protein S (PS)....

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Why Express Factors in Percent?

This is from Ann McConnell, East Carolina University, first posted on November 19: Why are factor activity assays reported in the range of 50%–150%? I am having a difficult time wrapping my mind around...

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FVIII Linearity; LA Testing

From Mahnaz Sairi, Associate Director of Hematology,  MBHN: Hi George: What is the highest limit we can report For FVIII? And how we determine this? Is it by clinical significance or by instrument...

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Delta Checks for PT,PTT, Fg, and D-dimer

Lisa Ledford at Duncan Regional Hospital asks, Would you be willing to share your δ-check values for the following tests? PT/INR PTT Fibrinogen D-dimer Thanks, Lisa Hi, Lisa, I checked with Warren...

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D-dimer of 0.0 ng/mL?

From Joanna Carroll, MT (ASCP), North Carolina State University College of Veterinary Medicine. We are running automated D-dimers and recently got a result of 0.00 ng/mL. Have you seen a value reported...

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We Are Current

George has caught up with our lost posts from November 2–24 and with our subsequent posts. If you have sent me a message or a comment and you don’t see it here, please re-send it and I will get it...

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Anti-Xa Calibrators

This post comes from Scott Miller, St. Mary’s of Michigan: We will soon be validating our activated partial thromboplastin time (APTT, PTT) heparin therapeutic range by using a comparison between an...

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October Cheat Sheet Restored

Our recent crash wiped out our October Cheat Sheet, the monthly summary of October posts. While the Sheet has been delivered via “push” email to our participants, you may wish to use it on the site in...

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BD Recalls Citrate Tubes

From Kelly Townsend at Tricore Reference Laboratories in Albuquerque: Just got a letter stating that BD Vacutainer is recalling a lot of their 2.7 mL sodium citrate tubes due to lithium heparin...

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FDA Requires Precise Heparin Label

Elaine Benoit, Precision BioLogic, sent an FDA alert regarding a heparin label change. “This label change will require manufacturers of Heparin Lock Flush Solution, USP and Heparin Sodium Injection,...

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